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OT-treating nail fungus with ethylene

glycol(antifreeze).I know this was discussed before but I can't find it.
Has anyone actually tried this? Do you soak the toe or 'paint' it on? For how long?


  • Simple really, Couple drops on/around
    -- Last Updated: Dec-21-05 1:37 PM EST --

    the infected toe nail in the morning and again at night. A whole heck of a lot less toxic than treating the whole body with poison like those pills do. You know the ones ... may effect kidneys, liver ...

    This treatment was found by accident when it was discovered antifreeze would clear wood and things of insects, eggs, so on and so forth in a much, much shorter time than other methods. Museums were using this to get things into the displays in weeks instead of months and years.

    Unexpected benefit for those doing the treatment was their nail fungus were all gone!!!

    I last looked it up thru google search using something like "antifreeze treatment of wood", Antifreeze fungus toe nail", and variations of these. I did find the original article and used that info to post the treatment the article suggested to a threat here.

    Hope it works as good for you as it has for others!



  • Thanks Mick.
  • Any time! Oh, just found another ...

    I have a 60+ year old case of the fungus infection known as "athlete's foot". Many years ago it infected the toenails extensively. The whole thing was pretty grotesque. My dermatologist and druggist both assured me there is no known cure. About six years ago I started using antifreeze applied under the nails with a medicine dropper about every five days. The professionals are technically right. I have not completely cured it, but the nails have grown out pink and thinned almost to the ends and I never have any trouble with blistering, peeling, or itching between the toes as I had had for six decades. No drug company is going to have any interest in this because the information has been in the public domain for so long that there is no opportunity for any proprietary advantage. The various wood-rotting organisms cannot be anywhere near as tough.
  • You can also try........
    just regular distilled white vinegar, or Australian tea tree oil which can be found in more places than you think. Try an herbal store if you can't find it anywhere else.
    It's good to have so many "natural" alternatives isn't it?

    Mick is right. These are the type things that Doctors, and Drug companies would never want you to know. There are a zillion natural cures for such things. And most of them are just as, if not more effective than today's modern medicine.

    What's unfortunate is that the drug cure for nail fungus can cause serious damage to your liver. Doctors will order liver tests done while you are on this medication. When the cure is potentially that much worse than the ailment itself? No thanks!

    Good luck! Splash
  • Anti-Freeze
    Ethylene glycol (EG) is not exactly harmless. In your body your liver in particular converts ethlene glycol to highly reactive molecules that damage the liver, kidney and other organs. Some solvents like EG are useful for dissolving drugs so they can penetrate your skin. Unfortunately anti-freeze contains lots of other chemicals which I do not know the toxicity. If you read the label on the antifreeze you are using it will warn you it is a highly toxic mixture. EG can transport that mixture through your skin. I would go to my doctor and get a prescription for a topical fungicide before I put antifreeze on my toe on a regular basis. Doubtful getting anti-freeze on your skin is going to kill you, but if you have an infected or damaged area under the nail you may cause more harm than good. The safety and efficacy of fungicide is well known in controlled clinical tests and that's what you are paying for.
  • The view point of toxicity and risk.
    -- Last Updated: Dec-21-05 3:25 PM EST --

    Those topical meds whether over the counter or prescription just plain DO NOT WORK!!! If you have ever had a bad case you would not even mention topical.

    As for the internal prescriptions (the pills) I have been on them three times. Each was for 6 to 12 months. Each lasted about 5 or 6 years. NOW go read the problems with those pills, AND talk to your pharmacist about them.

    I will take external ethylene glycol anytime over those extremely poisonous pills again. Been advised by many medical personal (Drs, Pharmacist, toxicology specialists, etc.) that I should never take those pills again. I will take almost any external treatments over internal meds anytime.

    Let us know what your doctor or more importantly your pharmacist tells you about the comparative dangers. (BTW: in case you did not know, pharmacist are much more knowledgeable than doctors about their drugs and will give you better information almost every time.)



  • listerine
    Sometime this summer someone sent a list of little known cures.

    Listerine for toenail fungus was on the list.

    Immediately it stops the itching between my toes. It isn't an overnight cure for a badly infected toe but it does seem to have positive results.

    It helps to put the listerine in something that can be rolled up over your foot and just go to bed wearing it so that it soaks into the infected parts of the toe overnight.

    My toes look like they might be getting better.

  • You are right
    I know nothing about drugs and toxicity.

    Good luck.
  • Options
    My Mon gave me tea tree oil to
    take on a river trip last Summer...I got bit by a bug I never saw and jeeze did it sting..I put the oil on it and in a few minutes I was much better...I also rubbed some into my hands that were weathered and dry, really helped a lot..
  • try
    Vicks Vapor rub for toe nail fungus
  • Options
    -- Last Updated: Dec-22-05 9:25 AM EST --

    Ethylene glycol when ingested causes oxalate stones and can kill you. Using it topically on broken skin of athletes feet is dangerous in my opinion.

    Lamisil is number one for treatment of athletes feet and toenail fungus currently.

    I cured a toenail fungus (rapidly) a couple years ago using chlorhexidine gluconate, a commonly used antiseptic for surgeons scrubbing in to surgery. You can find it in a product called Hibiclens. What needs to be developed is a method of nail debridement followed by topical treatment with chlorhexidine gluconate. The debridement would need to be either peeling off part of the nail to expose the infected layer of the nail or drilling shallow holes in the nail. In my case I peeled off the top part of the nail, scrubbed it with this chemical, and it was growing normal nail in two weeks. I was shocked to say the least.

    ADD IN:
    Only a medical professional should be drilling on nails!

  • Options
    the vicks vaporub works, ask Dr. Gott
  • THANKS!!!!!!!!!!!!!!
    -- Last Updated: Dec-22-05 6:44 AM EST --

    I knew the antifreeze method was not the safest, but still liked it over the other toxic methods, including lamisil. Been through lamisil and a couple of other toxic internal treatments. Was not lasting and was told not to do it again.

    Acetone (Asorbing Jr or straight acetone) was always a temporary, but effective in the meanwhile treatment. Never favored the bleach soaks. Vinegar was interesting, but temp and stinks. And so on ...

    You have given me (us) the first sensible, apparently nontoxic treatment that would seem to do a complete job.

    Thanks again and thank you String for bringing the subject up again!



  • Thanks everyone for the input.
    I'll try the less toxic stuff.
  • My wife tried the Tea Tree oil ..
    but it didn't work.
    It sure as hell smelled like we spilled turpintine around the house every night though.

    Jack L
  • Options
  • it's called onychomycosis..
    -- Last Updated: Dec-22-05 2:56 PM EST --

    and none of the "home remedies" listed here or otherwise will be very effective.

    the infection is systemic and concentrated at the nail bed. the nail plate (toenail) is impermeable to virtually all topicals. this is a kayak board so i'll give you a kayak simile: it'd be like trying to remove adhesive residue on the inside your cockpit by pouring acetone on the outside of the hull.

    there is one topical, Penlac, that has fda approval. take a look at it's clinical research: about an 11% cure rate with a pretty high rate of recurrence. doesn't sound too good to me.

    lamisil and sporanox are internals with some pretty serious side effects and toxicity issues and even then they still have 60%+ recurrence rates...not to mention they're bloody expensive. btw: lamisil's otc cream is not the same nor is it intended to treat the same condition as the pills.

    basically if you've had it for a while, suck it up and live with it. use topical otc antifungal creams on the remaining uninfected fingers and toes to help prevent spreading. if you suffer trauma (cracking, lifting, etc) to any nail treat it regularly with any otc antifungal to prevent infection. that's about it.....

    it comes down to the fact that onychomycosis (nail fungus) is kinda yicky and ugly but otherwise totally benign. leave it alone, keep it from spreading and get on with your life.

    full disclosure: I am not a physician, but I have been sponsoring and working on a cure for onychomycosis for 5 years at a major university hospital.

    disclaimer: the information above is worth precisely what you paid for it. please consult a physician if you suspect that you have nail fungus or any other health condition.....

  • Options
    This thread
    is extremely informative, but I wish we had those emoticon faces on this board cuz I'd use the green smilie barf face one at this moment.

    Squeemish on the west coast sends...
  • Options
    -- Last Updated: Dec-22-05 5:02 PM EST --

    Well, I have a medical degree to back up my experience with my nail fungus. You should get your guys to try my method in clinical trials instead of believing it's always going to be incurable. Prevention is very important in making sure it is not recurrent.

  • A Podiatrist Says...
    I was in a casual conversation with a podiatric surgeon today, and asked him about the EG thing. He raised his eyebrows, allowed as how it might be an effective topical agent, but if the infection gets down to the nail bed, or in very far, it is likely to be a systemic infection which would not respond to topical treatments. Not too serious, in any event.
    FWIW, Jeff
  • didn't see your method there....
    it would probably work as well with a common otc antifungal--perhaps best with one in an acetone base.

    of course, it only works if there is some clear nail to work with--as in catching it early. an advanced case is probably a lost cause.

    fyi: nearly an identical method to yours and a few other similar ones (including our own) have already been patented.
  • Options
    -- Last Updated: Dec-23-05 1:54 AM EST --

    Mine had no clear nail (looked to be total dystrophic type of OM), had been totally involved for several years and did not respond to two courses of Lamisil. Lamisil had worked in the past for me when another nail was partially involved. My nail was yellow and thick from proximal to distal, but it would peel off seemingly all the way to the nailbed. I know if sounds weird. I was astounded myself. If you can get the topical to the plane of infection, it may be able to penetrate throughout the plane of infection because that plane is weakened by the fungus and is not like normal nail.

    What is there to patent about my method other than some instrument to do the nail debridement with. Anybody can buy chlorhexidine gluconate. I suppose some company could rename the chemical and and just not label it what it is.

  • I tried several otc creams for fungal infections during the year, but it didn't help me. In the end, this remedy helped me: I soaked my big toe in one part vinegar one part listerine for 30 min a day. It took about 5-6 months for the fungus to clear up. I basically had to just wait until a whole new nail grew out. I could tell it was working because the base of the nail was clear when it started to grow out. So I just kept at it until it was completely grown out/gone before I stopped soaking.

  • RexRex
    edited December 2018

    Twice I have had a big toe nail turn brown. Twice I have used vinegar and water to make it go away. A little skin lotion spread on occasionally to keep the nail soft. It takes a long time but it works. If I remember correctly the first time I used a 50/50 mix of vinegar and water and applied it with a Q tip morning and night. The 2nd time I think I used more vinegar and less water. Any cheap skin lotion spread on occasionally will keep the nail from getting brittle. Hope you have the results I did.

  • Penlac worked for me once on a toe after multiple months. Then I got that stuff on TV foget the name perscription liquid. It worked. It was 500 plus for tiny tiny bottle. Used two of them. Doctor told me cure rate is 17% lol got a grand mind bending. Best prevetion throw out all your cotton socks..

  • It was Jublia was what I used. Crazy price. Bottle was half the size of my pinky and half empty when new.

  • RexRex
    edited December 2018

    Cost... you can't get much cheaper than vinegar... and toxicity... well it's on our healthy salads.

    A middle toe nail got really thick. Dermatologist said there was no vinegar fix for it. Just clip it and file it.

  • Vicks Vapo Rub
    It will cure toe nail fungus
    but may keep all but your most devoted fans away

  • Problem is penetrating the nail. Vapor rub isn't doing it.

  • @kayamedic said:
    Vicks Vapo Rub
    It will cure toe nail fungus
    but may keep all but your most devoted fans away

    I don't have any foot sniffing friends.

  • @PaddleDog52 said:
    Problem is penetrating the nail. Vapor rub isn't doing it.

    We tried it from hearsay.
    Then we checked with primary care provider who said that over the long run it works.
    You a doc? I know not all docs agree.

  • If it was working Vicks could repackage it and sell to make millions. It's BS.

  • My insurance company didn't spend 1200 plus with my doctor for Jublia if vapor rub worked. Jublia was months long process to work.

  • I'd rather try Vicks than antifreeze g y day.

  • This thread is starting to grow on me.

  • edited December 2018

    Paddle Dog has not found the edit button
    And I know what has worked for me
    Why sid this thread rise from the dead?

  • @Sparky961 said:
    This thread is starting to grow on me.


  • edited January 1

    Propylene glycol is a non-toxic antifreeze and is used in some nail fungus meds, though I don't know if its an active ingredient or just the solvent/carrier. And the bonus: you can also use it as an oral drench for ketosis in your pet cow.

    @ said:
    This thread
    is extremely informative, but I wish we had those emoticon faces on this board cuz I'd use the green smilie barf face one at this moment.

    Squeemish on the west coast sends...

    So this :p is not the one you were looking for to express your feelings on toe fungus? Are you sure? :p How about this one :#

  • While things approved by the FDA are not 100% safe I would recommend going with any treatment that your doctor recommends over ethylene gylcol.

    First of all it's an alcohol that is an irritant and can macerate your skin providing another source of infection. The reason why it may kill the fungus is that it's generally toxic and not as specific, so while the antifungals have some side effects, not that bad, and that can be monitoried easily, the antifreeze just dissolves and kills everything.

    Look up "drinking antifreeze". It's not safe. In the quantities you'd put on your finger I don't think it would be that bad but a fatal dose is not that much.

    Also please look up "antifreeze disposal". It's considered a hazmat item, albeit a lesser one. At least put something in your body that was designed to be there, however side effect prone, versus something that is a known human poison.

    That said I had a bad case of toenail fungus years ago because I was working long hours with big, thick shoes. Toenail fungus is due to excess moisture. Make sure you apply talcum powder, always wear socks, change foot wear at least once daily such that a pair of shoes or boots is never worn more than one day in a row and never twice per week allowing it to dry. By switching to Geox brand name shoes that "breahe" I basically cured my foot (and toenail fungus) problems without ever resorting to meds or creams.

    A little knowledge is a dangerous thing. For your own sake please seek the help of a qualified healthcare professional!

  • Ten drops of gas and a match daily and it will be gone after a two week period. Puff!

  • @CA 139 You wrote:

    " I basically cured my foot (and toenail fungus) problems without ever resorting to meds or creams."

    You must have had a mighty wimpy strain of cootie if you could make it go away with just dry shoes and talcum powder. I think most folks get a tougher bug.

  • Fungi nail from Walmart.

  • edited January 3

    @Rex said:
    @CA 139 You wrote:

    " I basically cured my foot (and toenail fungus) problems without ever resorting to meds or creams."

    You must have had a mighty wimpy strain of cootie if you could make it go away with just dry shoes and talcum powder. I think most folks get a tougher bug.

    No, it was the worst case of foot and skin fungus (not counting people that get inner fungal infections, I mean like septic joints, fungal meningitis, fungal abscesses, fungus in the lungs of different kinds and/or opportunistic HIV infections) I have ever seen in my nearly 20 year career as a physician. Most of my nails were involved which was one problem (onychomycosis) and a huge amount of the surface area of my feet was all red, scabbed, irritated, cracking and itchy being another problem (tinea pedis).

    This was from working 24-30 hour shifts during residency while wearing clogs which were stupidly recommended to me by others glowing reviews who were not in my field and working my hours. I see the same type of problem in people who work long hours on their feet, especially if they keep wearing the same pair or two of boots or shoes.

    The truth is that yeast is supposed to live in your skin and should not overgrow unless you subject that body area to excess enclosed moisture like wearing the same pair of moist shoes repeatedly. The meds will work short to intermediate term but these issues tend to be from an underlying cause which addressed can keep it from coming back which is what the ventilated Geox shoes did.

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