Is this trip doable? Northern Va canoe??

I’m trying to plan an overnight canoe trip for this summer. My plan is to put in at Watermelon park near Berryville VA. and then canoe to Harpers Ferry WV. and then get on the Potomac and go down to goose creek where I know of a spot that I can take out at. There are some stretches of this trip that I’m not familiar with and I was wondering if this is a possible stretch to canoe through with an overnight load?